Intern, Cryo-Electron Microscopy Structural Biologist
About Biogen:
At Biogen, our mission is clear - we are pioneers in neuroscience. Biogen discovers, develops, and delivers worldwide innovative therapies for people living with serious neurological and neurodegenerative diseases. Together, our employees create, commercialize, and manufacture transformative therapies for our patient population.
We at Biogen are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients who we serve. We are focused on strengthening our foundation to advance our overall Diversity, Equity and Inclusion (DE&I) strategy and, most importantly, ensure all our employees feel included.
As an intern at Biogen, you can expect to be placed on a real project, under the guidance of experienced professionals and subject matter experts who are invested in your career and academic growth. We also ensure that you have plenty of opportunities to build your network, learn more about our organization through weekly lunch and learns led by leaders from across the company, and join us for several fun events.
Summary
This application is for an internship role from June - August 2023. Resume review begins in January 2023.
We are looking for a highly motivated trainee to join our Structural Biology group within the department of Biotherapeutic and Medicinal Sciences at Biogen. Specifically, we establish and apply structural biology techniques to better understand target mechanisms and inform drug discovery decisions. We have in-house high-resolution structural biology technologies, including a Glacios cryo-EM microscope equipped with a BioQuantum K3 detector. This is a great opportunity to join a fast-paced and innovative community striving to impact unmet medical needs in neuroscience.
Position Description
As an intern, your primary role will be to prepare cryo-EM grids, assist with data collection, and solve structures of gene therapy-related technologies. You will also have opportunities to help establish cryo-EM workflow standards and implement and automate new processing software. You will also have:
- Experience with cryo-EM sample preparation and data collection
- Experience using Relion, cryoSPARC or other cryo-EM data processing programs
- Familiarity with Linux operating systems
- Experience with AAV gene therapy technology is a plus
- Ability to work independently, as well as in a team environment
- Be responsible, organized, and possess strong attention to detail
- Strong time management and organizational skills
- Strong communication and interpersonal skills
Qualifications:
To participate in the Biogen Internship Program, students must meet the following eligibility criteria:
- Legal authorization to work in the U.S.
- At least 18 years of age prior to the scheduled start date
- Be currently enrolled in an accredited college or university
Education
Current graduate students pursuing Master's or Ph.D. degrees in Biophysics, Biochemistry or related discipline interested in a 12-week internship.
Location
Cambridge, MA